Assoc. Prof. (PD) Dr. med. Dr. med. univ. Georg Marcus Fröhlich

 

Scientific achievements

Research
TAVR (GALILEO, EARTH TAVI studies at the Charité Berlin, Germany)
Improve outcome after a heart attack

(Hatter Institute - University College London, England)

Fractional flow reserve, pressure wire assessment
Heart failure, Unispital Zürich

 

Deputy Editor

on behalf of the Cardiology Journal  “Open Heart” – British Medical Journals, London, United Kingdom

 

Numerous scientific talks attending national and international conferences

 

List of publications

 

Leistner DM, Landmesser U, Fröhlich GM. FD-OCT and IVUS for detection of incomplete stent apposition in heavily calcified vessels: novel insights. Open Heart. 2015 Dec 22;2(1):e000292. doi: 10.1136/openhrt-2015-000292. eCollection 2015.

 

Braune S, Fröhlich GM, Lendlein A, Jung F. Effect of temperature on platelet adherence. Clin Hemorheol Microcirc. 2016;61(4):681-8.

 

Fröhlich GM, Baxter PD, Malkin CJ, Scott DJ, Moat NE, Hildick-Smith D, Cunningham D, MacCarthy PA, Trivedi U, de Belder MA, Ludman PF, Blackman DJ;National Institute for Cardiovascular Outcomes Research. Comparative survival after transapical, direct aortic, and subclavian transcatheter aortic valve implantation (data from the UK TAVI registry). Am J Cardiol. 2015 Nov 15;116(10):1555-9.

 

Fröhlich GM, Landmesser U. Thrombus aspiration in STEMI revisited: impact on Coronary microcirculation? Open Heart. 2015 Jun 17;2(1):e000274. doi: 10.1136/openhrt-2015-000274. eCollection 2015.

 

Bulluck H, Fröhlich GM, Mohdnazri S, Gamma RA, Davies JR, Clesham GJ, Sayer JW, Aggarwal RK, Tang KH, Kelly PA, Jagathesan R, Kabir A, Robinson NM, Sirker A, Mathur A, Blackman DJ, Ariti C, Krishnamurthy A, White SK, Meier P, Moon JC, Greenwood JP, Hausenloy DJ. Mineralocorticoid receptor antagonist pretreatment to MINIMISE reperfusion injury after ST-elevation myocardial infarction (the MINIMISE STEMI Trial): rationale and study design. Clin Cardiol. 2015 May;38(5):259-66.

 

Fröhlich G, Landmesser U. [Myocardial revascularization: the new European guidelines]. Dtsch Med Wochenschr. 2015 Apr;140(7):

 

Reinthaler M, Schwabe A, Landmesser U, Chung R, Aggarwal S, Delahunty N, Fröhlich G, Meier P, Roberts N, Pantazis A, Mullen MJ. 'Paradoxical' low-flow,

low-gradient severe aortic valve stenosis: an entity with limited improvement following transcatheter aortic valve implantation. J Heart Valve Dis. 2014 Jul;23(4):441-9.

 

Reinthaler M, Stähli BE, Gopalamurugan AB, Xiu PY, Aggarwal SK, Fröhlich G, Delahunty N, Mullen MJ. Post-procedural arterial hypertension: implications for

clinical outcome after transcatheter aortic valve implantation. J Heart Valve Dis. 2014 Nov;23(6):675-82.

 

Reinthaler M, Aggarwal SK, De Palma R, Landmesser U, Froehlich G, Yap J, Meier P, Mullen MJ. Predictors of clinical outcome in transfemoral TAVI: circumferential iliofemoral calcifications and manufacturer-derived recommendations. Anatol J Cardiol. 2015 Apr;15(4):297-305.

 

White SK, Frohlich GM, Sado DM, Maestrini V, Fontana M, Treibel TA, Tehrani S, Flett AS, Meier P, Ariti C, Davies JR, Moon JC, Yellon DM, Hausenloy DJ. Remote ischemic conditioning reduces myocardial infarct size and edema in patients with ST-segment elevation myocardial infarction. JACC Cardiovasc  Interv. 2015 Jan;8(1 Pt B):178-88.

 

Fröhlich GM, Redwood S, Rakhit R, MacCarthy PA, Lim P, Crake T, White SK, Knight CJ, Kustosz C, Knapp G, Dalby MC, Mali IS, Archbold A, Wragg A, Timmis AD, Meier P. Long-term survival in patients undergoing percutaneous Interventions with or without intracoronary pressure wire guidance or Intracoronary ultrasonographic imaging: a large cohort study. JAMA Intern Med. 2014 Aug;174(8):1360-6.

 

Reser D, Fröhlich GM, Seifert B, Lachat ML, Jacobs S, Enseleit F, Ruschitzka F, Falk V, Wilhelm MJ. The impact of pretransplantation urgency status and the presence of a ventricular assist device on outcome after heart transplantation. Transplant Proc. 2014 Jun;46(5):1463-8.

 

Fröhlich GM, Lansky AJ, Webb J, Roffi M, Toggweiler S, Reinthaler M, Wang D, Hutchinson N, Wendler O, Hildick-Smith D, Meier P. Local versus general anesthesia for transcatheter aortic valve implantation (TAVR)--systematic review and meta-analysis. BMC Med. 2014 Mar 10;12:41.

 

Fröhlich GM, Schoch B, Wolfrum M, Osranek M, Enseleit F, Herzog BA, Hasun M, Lüscher TF, Meier P, Gaemperli O, Kaufmann PA, Corti R. The impact of Modern noninvasive cardiac imaging on coronary intervention rates. J Interv Cardiol. 2014 Feb;27(1):50-7.

 

Bahl R, Indermuehle A, Froehlich GM, Lansky AJ, Knapp G, Timmis A, Meier P. Drug-eluting balloon for instent restenosis--the author's reply. Heart. 2013 Dec;99(24):1874-5.

 

Raess M, Fröhlich G, Roos M, Rüsi B, Wilhelm MJ, Noll G, Ruschitzka F, Fehr T, Enseleit F. Donor-specific anti-HLA antibodies detected by Luminex: predictive for short-term but not long-term survival after heart transplantation. Transpl Int. 2013 Nov;26(11):1097-107.

 

Fröhlich GM, Holzmeister J, Hübler M, Hübler S, Wolfrum M, Enseleit F, Seifert B, Hürlimann D, Lehmkuhl HB, Noll G, Steffel J, Falk V, Lüscher TF, Hetzer R, Ruschitzka F. Prophylactic implantable cardioverter defibrillator treatment in patients with end-stage heart failure awaiting heart transplantation. Heart. 2013 Aug;99(16):1158-65.

 

Meier P, Wolfrum M, Froehlich GM, Casaubon LK, Lansky AJ.Heart. 2013 Oct;99(20):1543.

 

Meier P, Fröhlich GM, Lansky AJ. Bleeding complications in percutaneous coronary interventions. Cardiology. 2013;125(4):213-6.

 

Wolfrum M, Froehlich GM, Knapp G, Casaubon LK, DiNicolantonio JJ, Lansky  AJ, Meier P. Stroke prevention by percutaneous closure of patent foramen ovale:  A systematic review and meta-analysis. Heart. 2014 Mar;100(5):389-95.

 

Fröhlich GM, Lansky AJ, Ko DT, Archangelidi O, De Palma R, Timmis A, Meier P. Drug eluting balloons for de novo coronary lesions - a systematic review and meta-analysis. BMC Med. 2013 May 8;11:123.

 

Meier P, Fröhlich GM, Meller S, De Palma R, Lansky AJ. Selection and timing for invasive therapy in non-ST-segment-elevation acute coronary syndrome. Expert Rev Cardiovasc Ther. 2013 Apr;11(4):437-45.

 

Fröhlich GM, Meier P, White SK, Yellon DM, Hausenloy DJ. Myocardial reperfusion injury: looking beyond primary PCI. Eur Heart J. 2013 Jun;34(23):1714-22.

 

Fröhlich GM, Enseleit F, Wolfrum M, von Babo M, Frank M, Berli R, Hermann M, Holzmeister J, Noll G, Lüscher TF, Ruschitzka F, Rufibach K, Wilhelm M, Falk V.

Response to letters regarding article, “statins and the risk of cancer after heart transplantation”. Circulation. 2013 Feb 5;127(5):e442.

 

Fröhlich GM, Keller P, Schmid F, Wolfrum M, Osranek M, Falk C, Noll G, Enseleit F, Reinthaler M, Meier P, Lüscher TF, Ruschitzka F, Tanner FC. Haemodynamically irrelevant pericardial effusion is associated with increased mortality in patients with chronic heart failure. Eur Heart J. 2013 May;34(19):1414-23.

 

Indermuehle A, Bahl R, Lansky AJ, Froehlich GM, Knapp G, Timmis A, Meier P. Drug-eluting balloon angioplasty for in-stent restenosis: a systematic review and meta-analysis of randomised controlled trials. Heart. 2013 Mar;99(5):327-33.

 

Fröhlich GM, Lyon RM, Sasson C, Crake T, Whitbread M, Indermuehle A, Timmis A, Meier P. Out-of-hospital cardiac arrest -optimal management. Curr Cardiol Rev.2013 Nov;9(4):316-24. Review.

 

Froehlich G, Crake T, Meier P. Exercise training for refractory angina: improving the coronary collateral circulation. Cardiology. 2012;123(2):78-9; author reply 80

 

Meier P, Froehlich GM, Yellon DM, Hausenloy DJ. Predicting peri-procedural myocardial infarction during PCI. Heart. 2012 Oct;98(20):1471-2.

 

Fröhlich GM, Rufibach K, Enseleit F, Wolfrum M, von Babo M, Frank M, Berli R, Hermann M, Holzmeister J, Wilhelm M, Falk V, Noll G, Lüscher TF, Ruschitzka F.Statins and the risk of cancer after heart transplantation. Circulation. 2012 Jul 24;126(4):440-7.

 

Enseleit F, Sudano I, Périat D, Winnik S, Wolfrum M, Flammer AJ, Fröhlich GM, Kaiser P, Hirt A, Haile SR, Krasniqi N, Matter CM, Uhlenhut K, Högger P,  Neidhart M, Lüscher TF, Ruschitzka F, Noll G. Effects of Pycnogenol on Endothelial function in patients with stable coronary artery disease: a double -blind, randomized, placebo-controlled, cross-over study. Eur Heart J. 2012Jul;33(13):1589-97.

 

Fröhlich GM, Schoch B, Schmid F, Keller P, Sudano I, Lüscher TF, Noll G, Ruschitzka F, Enseleit F. Takotsubo cardiomyopathy has a unique cardiac  Biomarker profile: NT-proBNP/myoglobin and NT-proBNP/troponin T ratios for the Differential diagnosis of acute coronary syndromes and stress induced cardiomyopathy. Int J Cardiol. 2012 Feb 9;154(3):328-32.

 

Fröhlich G, Steffel J, Hürlimann D, Enseleit F, Lüscher TF, Ruschitzka F, Abraham WT, Holzmeister J. Upgrading to resynchronization therapy after Chronic right ventricular pacing improves left ventricular remodelling. Eur Heart J. 2010 Jun;31(12):1477-85.

 

Fröhlich G, Kaplan V, Amann-Vesti B. Holy fire in an HIV-positive man: a case of 21st-century ergotism. CMAJ. 2010 Mar 9;182(4):378-80.

 

Seyfarth M, Sibbing D, Bauer I, Fröhlich G, Bott-Flügel L, Byrne R, Dirschinger J, Kastrati A, Schömig A. A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock caused by myocardial infarction. J Am Coll Cardiol. 2008 Nov 4;52(19):1584-8.

 

Fröhlich G, Pörner M, Wessely R. Images in cardiovascular medicine. Aortic coarctation visualized by 16-row detector multislice computed tomography. Circulation. 2005 Aug 9;112(6):e81.

 

Fröhlich G, Strehblow C, Sperker W, Yahya N, Shirazi M, Hevesi A, Garamvölgyi R, Hadjiev J, Scherzer T, Glogar D, Gyöngyösi M. Serial intravascularultrasonographic measurements after implantation of biodegradable polymer coated stents in porcine coronary arteries. Coron Artery Dis. 2003 Aug;14(5):409-12.